Wednesday, September 28, 2016

Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup


Pronunciation: KAR-bin-OX-a-meen/METH-skoe-POL-a-meen/SOO-doe-e-FED-rin
Generic Name: Carbinoxamine/Methscopolamine/Pseudoephedrine
Brand Name: Examples include Pannaz S and Pseudox M


Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup is used for:

Relieving congestion, sneezing, runny nose, and itchy, watery eyes due to colds, flu, or hay fever. It may also be used for other conditions as determined by your doctor.


Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup is an antihistamine, decongestant, and anticholinergic combination. It works by blocking histamine, a substance in the body that causes sneezing, runny nose, and watery eyes. It also relieves nasal congestion by shrinking the nasal mucous membranes, which promotes nasal drainage, and dries the chest by decreasing lung secretions.


Do NOT use Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup if:


  • you are allergic to any ingredient in Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup

  • you are pregnant or breast-feeding

  • you take sodium oxybate (GHB) or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

  • you have severe heart blood vessel disease; severe high blood pressure; narrow-angle glaucoma; severe bleeding; severe irritation of the esophagus or other serious problems with the esophagus (eg, esophageal achalasia); peptic ulcer; a blockage of your stomach, bowel, or bladder; bowel motility problems; severe bowel inflammation (eg, ulcerative colitis); certain muscle problems (eg, myasthenia gravis); or uncontrolled bleeding

  • you are unable to urinate or are having an asthma attack

Contact your doctor or health care provider right away if any of these apply to you.



Before using Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup:


Some medical conditions may interact with Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have a history of diabetes, an enlarged prostate or other prostate problems, bladder or kidney problems, severe bowel problems, trouble urinating, high blood pressure, diarrhea, asthma, nerve problems, heart problems, blood vessel problems, blood clots, a hiatal hernia, an adrenal gland tumor, glaucoma, breathing problems during sleep, seizures, stroke, myasthenia gravis (muscle weakness), or an overactive thyroid

Some MEDICINES MAY INTERACT with Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Alpha-blockers (eg, guanethidine, methyldopa, prazosin), beta-blockers (eg, atenolol), diuretics (eg, furosemide, hydrochlorothiazide), furazolidone, or MAOIs (eg, phenelzine) because the risk of high or low blood pressure may be increased

  • Alkalizers (eg, calcium or magnesium antacids), anticholinergics (eg, atropine, benztropine, dicyclomine), carbonic anhydrase inhibitors (eg, acetazolamide), ergotamine, sodium bicarbonate, or tricyclic antidepressants (eg, amitriptyline) because they may increase the risk of Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup's side effects

  • Bromocriptine, catechol-O-methyltransferase (COMT) inhibitors (eg, entacapone), certain stimulants (eg, doxapram, pseudoephedrine), cocaine, digoxin, droxidopa, potassium chloride, or sodium oxybate (GHB) because the risk of their side effects may be increased by Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup

  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup

This may not be a complete list of all interactions that may occur. Ask your health care provider if Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup:


Use Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Take Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.

  • Do not take Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup at the same time as an antacid, certain medicines for diarrhea (eg, attapulgite, bismuth, kaolin, pectin), or ketoconazole. Take these medicines 2 or 3 hours before or after you take Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup.

  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.

  • If you miss a dose of Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup.



Important safety information:


  • Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.

  • If your symptoms do not get better within 7 days or if they get worse or you develop a high fever or persistent headache, check with your doctor.

  • Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup may cause dry mouth. To relieve dry mouth, suck on sugarless hard candy or ice chips, chew sugarless gum, drink water, or use a saliva substitute.

  • Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup may make your eyes more sensitive to sunlight. It may help to wear sunglasses.

  • Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup may reduce sweating. Do not become overheated in hot weather or while you are being active; heatstroke may occur.

  • Do not take diet or appetite control medicines while you are taking Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup without checking with your doctor.

  • Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup has pseudoephedrine in it. Before you start any new medicine, check the label to see if it has pseudoephedrine in it too. If it does or if you are not sure, check with your doctor or pharmacist.

  • Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup for a few days before the tests.

  • If you have trouble sleeping, ask your doctor or pharmacist about the best time of the day to take Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup.

  • Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup may interfere with certain lab tests. Be sure your doctor and lab personnel know that you are taking Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup.

  • Tell your doctor or dentist that you take Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup before you receive any medical or dental care, emergency care, or surgery.

  • Diabetes patients - Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.

  • Use Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup with caution in the ELDERLY; they may be more sensitive to its effects.

  • Caution is advised when using Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup in CHILDREN; they may be more sensitive to its effects.

  • PREGNANCY and BREAST-FEEDING: It is not known if Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup while you are pregnant. Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup is found in breast milk. Do not breast-feed while taking Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup.


Possible side effects of Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; mental or mood changes; seizures; severe dizziness, lightheadedness, or headache; tremor; vision changes.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Carbinoxamine/Methscopolamine/Pseudoephedrine side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include deep sleep or loss of consciousness; hot or cool skin; irregular heartbeat; irritability, anxiety, or panic; large pupils; numbness or tingling in the arms or legs; seizures; slowed or shallow breathing.


Proper storage of Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup:

Store Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup out of the reach of children and away from pets.


General information:


  • If you have any questions about Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup, please talk with your doctor, pharmacist, or other health care provider.

  • Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Carbinoxamine/Methscopolamine/Pseudoephedrine Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Carbinoxamine/Methscopolamine/Pseudoephedrine resources


  • Carbinoxamine/Methscopolamine/Pseudoephedrine Side Effects (in more detail)
  • Carbinoxamine/Methscopolamine/Pseudoephedrine Use in Pregnancy & Breastfeeding
  • Carbinoxamine/Methscopolamine/Pseudoephedrine Drug Interactions
  • Carbinoxamine/Methscopolamine/Pseudoephedrine Support Group
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